PHYSICAL PHARMACEUTICS I
solubility of liquids in liquids, (Binary solutions, ideal solutions) Raoult’s law
PHYSICAL PHARMACEUTICS I
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Solubility of drugs
Solubility of drugs: Solubility expressions
Reading
mechanisms of solute solvent interactions, ideal solubility parameters
Reading
solvation & association, quantitative approach to the factors influencing solubility of drugs
Reading
diffusion principles in biological systems
Reading
Solubility of gas in liquids
Reading
solubility of liquids in liquids, (Binary solutions, ideal solutions) Raoult’s law
Reading
real solutions. Partially miscible liquids
Reading
Critical solution temperature and applications.
Reading
Distribution law
Reading
Distribution law, its limitations and applications
Reading
States of Matter and properties of matter
State of matter introduction
Reading
changes in the state of matter, latent heats
Reading
vapour pressure, sublimation critical point, eutectic mixtures, gases
Reading
aerosols – inhalers, relative humidity
Reading
liquid complexes, liquid crystals, glassy states
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solid- crystalline, amorphous & polymorphism.
Reading
Refractive index, optical rotation
Reading
dielectric constant
Reading
dipole moment, dissociation constant
Reading
determinations and applications
Reading
Surface and interfacial phenomenon:
Surface and interfacial phenomenon: Liquid interface
Reading
surface & interfacial tensions
Reading
surface free energy, measurement of surface & interfacial tensions
Reading
spreading coefficient
Reading
adsorption at liquid interfaces
Reading
surface active agents, HLB Scale
Reading
adsorption at solid interface
Reading
solubilisation, detergency
Reading
Complexation and protein binding
Complexation and protein binding: Introduction
Reading
Classification of Complexation, Applications
Reading
methods of analysis
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protein binding,
Reading
Complexation and drug action
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crystalline structures of complexes
Reading
thermodynamic treatment
Reading
thermodynamic treatment of stability constants
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pH, buffers and Isotonic solutions
Applications
Reading
pH, buffers and Isotonic solutions: Sorensen’s pH scale
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pH determination electrometric and calorimetric
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applications of buffers
Reading
buffer capacity
Reading
buffer equation
Reading
buffers in pharmaceutical and biological systems
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buffered isotonic solutions
Reading
Isotonic solutions
Reading
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Exercise Files
C6 SOLUBILITY OF LIQUIDS IN LIQUIDS, (BINARY SOLUTIONS, IDEAL SOLUTIONS) RAOULT’S LAW (docx)
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