BP104T. PHARMACEUTICAL INORGANIC CHEMISTRY (Theory)-45Hrs

About Course

Scope: This subject deals with the monographs of inorganic drugs and pharmaceuticals.
Objectives: Upon completion of course student shall be able to
 know the sources of impurities and methods to determine the impurities in inorganic
drugs and pharmaceuticals  understand the medicinal and pharmaceutical importance of inorganic compounds

Course Content

UNIT I 10 Hours
 Impurities in pharmaceutical substances: History of Pharmacopoeia, Sources and types of impurities, principle involved in the limit test for Chloride, Sulphate, Iron, Arsenic, Lead and Heavy metals, modified limit test for Chloride and Sulphate General methods of preparation, assay for the compounds superscripted with asterisk (*), properties and medicinal uses of inorganic compounds belonging to the following classes

UNIT II 10 Hours
Acids, Bases and Buffers: Buffer equations and buffer capacity in general, buffers in pharmaceutical systems, preparation, stability, buffered isotonic solutions, measurements of tonicity, calculations and methods of adjusting isotonicity.  Major extra and intracellular electrolytes: Functions of major physiological ions, Electrolytes used in the replacement therapy: Sodium chloride, Potassium chloride, Calcium gluconate and Oral Rehydration Salt (ORS), Physiological acid base balance.  Dental products: Dentifrices, role of fluoride in the treatment of dental caries, Desensitizing agents, Calcium carbonate, Sodium fluoride, and Zinc eugenol cement.

UNIT III 10 HOURS

UNIT IV 8 HOURS

UNIT V 7 HOURS

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