Course Content
UNIT I-Impurities in pharmaceutical substances-10hrs
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Impurities in pharmaceutical substances: History of Pharmacopoeia
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Impurities in pharmaceutical substances: History of Pharmacopoeia
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Impurities in pharmaceutical substances: Sources and types of impurities.
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Impurities in pharmaceutical substances: Principle involved in the limit test for Chloride, Sulphate.
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Impurities in pharmaceutical substances: Principle involved in the limit test for Iron .
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Impurities in pharmaceutical substances: Principle involved in the limit test for Arsenic .
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Impurities in pharmaceutical substances: Principle involved in the limit test for Lead .
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Impurities in pharmaceutical substances: Principle involved in the limit test for and Heavy metals.
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Modified limit test for Chloride.
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Modified limit test for Sulphate.
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UNIT II-Acids, Bases and Buffers-10hrs
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Acids, Bases and Buffers: Buffer equations and buffer capacity in general, buffers in pharmaceutical systems.
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Acids, Bases and Buffers: Preparation, stability, buffered isotonic solutions.
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Acids, Bases and Buffers: Measurements of tonicity
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Calculations and methods of adjusting isotonicity.
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Major extra and intracellular electrolytes: Functions of major physiological ions.
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Electrolytes used in the replacement therapy: Sodium chloride, Potassium chloride.
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Electrolytes used in the replacement therapy: Calcium gluconate and Oral Rehydration Salt (ORS), Physiological acid base balance.
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Dental products: Dentifrices, role of fluoride in the treatment of dental caries.
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Dental products: Desensitizing agents, Calcium carbonate.
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Dental products: Sodium fluoride, and Zinc eugenol cement.
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UNIT III-Gastrointestinal agents-10hrs
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Acidifiers: Ammonium chloride and Dil. HCl
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Antacid: Ideal properties of antacids, combinations of antacids.
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Antacid: Sodium 40 Bicarbonate, Aluminum hydroxide gel.
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Antacid: Magnesium hydroxide mixture
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Cathartics: Magnesium sulphate, Sodium orthophosphate.
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Cathartics: Kaolin and Bentonite.
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Antimicrobials: Mechanism, classification.
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Antimicrobials: , Potassium permanganate, Boric acid.
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Antimicrobials: Hydrogen peroxide, Chlorinated lime.
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Antimicrobials: Iodine and its preparations.
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UNIT IV-Miscellaneous compounds-8hrs
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Expectorants: Potassium iodide.
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Expectorants: Ammonium chloride.
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Emetics: Copper sulphate.
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Emetics: Sodium potassium tartarate.
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Haematinics: Ferrous sulphate, Ferrous gluconate.
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Poison and Antidote: Sodium thiosulphate.
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Poison and Antidote: Activated charcoal, Sodium nitrite 333.
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Astringents: Zinc Sulphate, Potash Alum.
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UNIT V- Radiopharmaceuticals.-7hrs
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Radiopharmaceuticals: Radio activity.
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Radiopharmaceuticals: Measurement of radioactivity.
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Properties of α, β, γ radiations.
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Radiopharmaceuticals: Half life, radio isotopes.
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Radiopharmaceuticals: Study of radio isotopes – Sodium iodide I131.
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Radiopharmaceuticals: Storage conditions, precautions.
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Radiopharmaceuticals: pharmaceutical application of radioactive substances.
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PHARMACEUTICAL INORGANIC CHEMISTRY-45Hrs
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