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PHYSICAL PHARMACEUTICS II BP403T
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4th Semester
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Course Content
UNIT-1
Introduction of colloids
Classification of dispersion systems, characteristics size shapes of colloidal particles
Classification of colloids & general properties
Optical properties
Kinetic properties
Electrical properties
Effect of electrolytes, coacervation, peptization and protective action
Stability of colloids
UNIT-2
Rheology Introduction Newtons law Non Newtonian systems
Pseudo plastic flow
Thixotropy
Determination of Rheological properties
MULTI POINT VISCOMETERS (ROTATIONAL)
ROTATIONAL VISCOMETERS
Deformation of solids
HECKEL EQUATION
STRESS,STRAIN,MODULUS
ANTI-THIXOTROPHY
UNIT-3
COARSE DISPERSIONS
CONTROLLED FLOCCULATION
Emulsions and theories of emulsification
Multiple emulsions
STABILITY OF EMULSION
Coalescence and breaking
Preservation of emulsions
UNIT-4
MICROMERITICS
Number and Weight Distributions
Methods for Determining Particle Size
Methods for Determining Particle Size
Methods for Determining Particle Size (Sedimentation)
Methods to determine particle size
Particle Shape and Surface Area
Methods for Determining Surface Area
Air Permeability Method
Derived Properties of Powders
UNIT-5
DRUG STABILITY ,Chemical Kinetics and Stability
Methods for determining the order of reaction
Factors affecting rate of reaction
Factors affecting rate of reaction
Catalysis
Accelerated stability and stress testing
Stability of pharmaceuticals
Oxidation
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