BP402T. MEDICINAL CHEMISTRY – I (Theory)

Scope: This subject is designed to impart fundamental knowledge on the structure,
chemistry and therapeutic value of drugs. The subject emphasizes on structure activity
relationships of drugs, importance of physicochemical properties and metabolism of
drugs. The syllabus also emphasizes on chemical synthesis of important drugs under each
class.
Objectives: Upon completion of the course the student shall be able to
1. understand the chemistry of drugs with respect to their pharmacological activity
2. understand the drug metabolic pathways, adverse effect and therapeutic value of
drugs
3. know the Structural Activity Relationship (SAR) of different class of drugs
4. write the chemical synthesis of some drugs
Course Content:
Study of the development of the following classes of drugs, Classification, mechanism of
action, uses of drugs mentioned in the course, Structure activity relationship of selective
class of drugs as specified in the course and synthesis of drugs superscripted (*)