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BP308P – PHARMACEUTICAL ENGINEERING (Practical)

Categories: 3rd Semester
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Course Content

I. Determination of radiation constant of brass, iron, unpainted and painted glass.

II. Steam distillation – To calculate the efficiency of steam distillation

III. To determine the overall heat transfer coefficient by heat exchanger

IV. Construction of drying curves (for calcium carbonate and starch)

V. Determination of moisture content and loss on drying

VI. Determination of humidity of air – i) From wet and dry bulb temperatures –use of Dew point method

VII. Description of Construction working and application of Pharmaceutical Machinery such as rotary tablet machine, fluidized bed coater, fluid energy mill, de humidifier.

VIII. Size analysis by sieving – To evaluate size distribution of tablet granulations – Construction of various size frequency curves including arithmetic andlogarithmic probability plots

IX. Size reduction: To verify the laws of size reduction using ball mill and determining Kicks, Rittinger’s, Bond’s coefficients, power requirement and critical speed of Ball Mil

X. Demonstration of colloid mill, planetary mixer, fluidized bed dryer, freeze dryer and such othermajor equipment

XI. Factors affecting Rate of Filtration and Evaporation (Surface area, Concentration and Thickness/ viscosity

XII. To study the effect of time on the Rate of Crystallization

XIII. To calculate the uniformity Index for given sample by using Double Cone Blender.

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