
About Course
BP601T. MEDICINAL CHEMISTRY – III (Theory)
Scope: This subject is designed to impart fundamental knowledge on the structure, chemistry and therapeutic value of drugs. The subject emphasis on modern techniques of rational drug design like quantitative structure activity relationship (QSAR), Prodrug concept, combinatorial chemistry and Computer aided drug design (CADD). The subject also emphasizes on the chemistry, mechanism of action, metabolism, adverse effects, Structure Activity Relationships (SAR), therapeutic uses and synthesis of important drugs.
Objectives: Upon completion of the course student shall be able to
1. Understand the importance of drug design and different techniques of drug
design.
2. Understand the chemistry of drugs with respect to their biological activity. 3. Know the metabolism, adverse effects and therapeutic value of drugs.
4. Know the importance of SAR of drugs
Course Content
UNIT-1 ANTIBIOTICS
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INTRODUCTION& CLASSIFICATION OF ANTIBIOTICS
00:00 -
Introduction,history, mechanism of action of pencillins
00:00 -
Classification, Mechanism of action and uses of pencillins
00:00 -
History, mechanism of action &classification of cephalosporins
00:00 -
SAR , Chemical degradation & uses of cephalosporins
00:00 -
Beta lactamase inhibitors
00:00 -
Monobactams
00:00 -
History, classification, mechanism of action of Tetracyclines
00:00 -
SAR of Tetracyclines, important products
00:00 -
Aminoglycosides
00:00