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BP501T. MEDICINAL CHEMISTRY – II (Theory) 45 Hours

Categories: 5th Semester
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About Course

Scope: This subject is designed to impart fundamental knowledge on the structure,

chemistry and therapeutic value of drugs. The subject emphasizes on structure activity

relationships of drugs, importance of physicochemical properties and metabolism of

drugs. The syllabus also emphasizes on chemical synthesis of important drugs under each

class.

Objectives: Upon completion of the course the student shall be able to

1. Understand the chemistry of drugs with respect to their pharmacological activity

2. Understand the drug metabolic pathways, adverse effect and therapeutic value of

drugs

3. Know the Structural Activity Relationship of different class of drugs

4. Study the chemical synthesis of selected drugs

Course Content

UNIT- I 10 Hours
Antihistaminic agents: and H1–antagonists:

  • Antihistaminic agents: Histamine, receptors and their distribution in the humanbody
    00:00
  • H1–antagonists
    00:00
  • H1–antagonists
    00:00
  • H2-antagonists
    00:00
  • Gastric Proton pump inhibitors
    00:00
  • Antineoplastic agents
    00:00
  • Antineoplastic agents
    00:00
  • Anti-neoplastic agents
    00:00
  • Anti-neoplastic agents
    00:00
  • Anti-neoplastic agents
    00:00

UNIT – II10 Hours
Anti anginal drugs, diuretics, antihypertensive

UNIT- III 10 hours
Anti-arrhythmic Drugs, anti hyperlipidemic, coagulants and anticoagulants, Drugs used in congestive heart failure

UNIT- IV 08 Hours
Drugs acting on Endocrine system,Sex hormones, Drugs for erectile dysfunction, Oral contraceptives, Corticosteroids,Thyroid and antithyroid drugs

UNIT – V 07 Hours
Antidiabetic agents, Local Anesthetics

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