BP808ET: CELL AND MOLECULAR BIOLOGY (Elective subject)

About Course

Scope:  Cell biology is a branch of biology that studies cells – their physiological
properties, their structure, the organelles they contain, interactions with their
environment, their life cycle, division, death and cell function.  This is done both on a microscopic and molecular level.  Cell biology research encompasses both the great diversity of single-celled
organisms like bacteria and protozoa, as well as the many specialized cells in
multi-cellular organismssuch as humans, plants, and sponges.
Objectives: Upon completion of the subject student shall be able to;  Summarize cell and molecular biology history.  Summarize cellular functioning and composition.  Describe the chemical foundations of cell biology.  Summarize the DNA properties of cell biology.  Describe protein structure and function.  Describe cellular membrane structure and function.  Describe basic molecular genetic mechanisms.  Summarize the Cell Cycle

Recommended Books (latest edition):
1. W.B. Hugo and A.D. Russel: Pharmaceutical Microbiology, Blackwell Scientific
publications, Oxford London.
2. Prescott and Dunn., Industrial Microbiology, 4th edition, CBS Publishers &
Distributors, Delhi.
3. Pelczar, Chan Kreig, Microbiology, Tata McGraw Hill edn.
4. Malcolm Harris, Balliere Tindall and Cox: Pharmaceutical Microbiology. 5. Rose: Industrial Microbiology. 6. Probisher, Hinsdill et al: Fundamentals of Microbiology, 9th ed. Japan
7. Cooper and Gunn’s: Tutorial Pharmacy, CBS Publisher and Distribution.
8. Peppler: Microbial Technology. 9. Edward: Fundamentals of Microbiology. 10. N.K.Jain: Pharmaceutical Microbiology, Vallabh Prakashan, Delhi
11. Bergeys manual of systematic bacteriology, Williams and Wilkins- A Waverly
company
12. B.R. Glick and J.J. Pasternak: Molecular Biotechnology: Principles and
Applications of RecombinantDNA: ASM Press Washington D.C.
13. RA Goldshy et. al., : Kuby Immunology.

Course Content

Unit I
a) Cell and Molecular Biology: Definitions theory and basics and Applications. b) Cell and Molecular Biology: History and Summation. c) Properties of cells and cell membrane. d) Prokaryotic versus Eukaryotic e) Cellular Reproduction f) Chemical Foundations – an Introduction and Reactions (Types)

Unit II
a) DNA and the Flow of Molecular Information b) DNA Functioning c) DNA and RNA d) Types of RNA e) Transcription and Translation

Unit III
a) Proteins: Defined and Amino Acids b) Protein Structure c) Regularities in Protein Pathways d) Cellular Processes e) Positive Control and significance of Protein Synthesis

Unit IV
a) Science of Genetics b) Transgenics and Genomic Analysis c) Cell Cycle analysis d) Mitosis and Meiosis e) Cellular Activities and Checkpoints

Unit V
a) Cell Signals: Introduction b) Receptors for Cell Signals c) Signaling Pathways: Overview d) Misregulation of Signaling Pathways e) Protein-Kinases: Functioning

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Course Content

Unit II a) DNA and the Flow of Molecular Information b) DNA Functioning c) DNA and RNA d) Types of RNA e) Transcription and Translation

Unit III a) Proteins: Defined and Amino Acids b) Protein Structure c) Regularities in Protein Pathways d) Cellular Processes e) Positive Control and significance of Protein Synthesis

Unit IV a) Science of Genetics b) Transgenics and Genomic Analysis c) Cell Cycle analysis d) Mitosis and Meiosis e) Cellular Activities and Checkpoints

Unit V a) Cell Signals: Introduction b) Receptors for Cell Signals c) Signaling Pathways: Overview d) Misregulation of Signaling Pathways e) Protein-Kinases: Functioning

Student Ratings & Reviews

Unit II
a) DNA and the Flow of Molecular Information b) DNA Functioning c) DNA and RNA d) Types of RNA e) Transcription and Translation

Unit III
a) Proteins: Defined and Amino Acids b) Protein Structure c) Regularities in Protein Pathways d) Cellular Processes e) Positive Control and significance of Protein Synthesis

Unit IV
a) Science of Genetics b) Transgenics and Genomic Analysis c) Cell Cycle analysis d) Mitosis and Meiosis e) Cellular Activities and Checkpoints

Unit V
a) Cell Signals: Introduction b) Receptors for Cell Signals c) Signaling Pathways: Overview d) Misregulation of Signaling Pathways e) Protein-Kinases: Functioning